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Article

Kruppel-like factor 6 germ-line mutations are infrequent in Finnish hereditary prostate cancer.

The Journal of urology - 1 Aug 2004

Koivisto Pasi A, Hyytinen Eija-R, Matikainen Mika, Tammela Teuvo L J, Ikonen Tarja, Schleutker Johanna

Abstract excerpt

PURPOSE: Recently, Kruppel-like factor 6 gene (KLF6) has been shown to be inactivated in up to 77% of prostate carcinomas. KLF6 has an important role in regulating cell growth and differentiation. The function and high mutation frequency in sporadic prostate carcinomas make KLF6 an attractive candidate for prostate cancer predisposition and, therefore, DNA samples from 69 Finnish prostate cancer families were...

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Source

Identifiers

PMID: 15247715
DOI: 10.1097/01.ju.0000129242.88182.e1

Genes

KLF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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