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Article

Inhibition of polyadenylation by stable RNA secondary structure

15 Apr 1998

Abstract excerpt

The presence of a polyadenylation signal in the repeat (R) region of the HIV-1 genome, which is located at both the 5' and 3' ends of the viral transcripts, requires differential regulation of polyadenylation. The HIV-1 poly(A) site can fold in a stable stem-loop structure that is well-conserved among different human and simian immunodeficiency viruses. In this study, we tested the effect of this hairpin on...

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PMID: 9518478
DOI: 10.1093/nar/26.8.1870

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Inhibition of polyadenylation by stable RNA secondary structurePMID 9518478Read ↗

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