Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Useful Bicistronic Reporter System for Studying Poly(A) Site-Defining cis Elements and Regulation of Alternative Polyadenylation.

International journal of molecular sciences - 17 Jan 2018

Deng Zhongyuan, Zhang Shen, Gu Shaohua, Ni Xinzhi, Zeng Wenxian, Li Xianchun

Abstract excerpt

The link between polyadenylation (pA) and various biological, behavioral, and pathological events of eukaryotes underlines the need to develop in vivo polyadenylation assay methods for characterization of the cis-acting elements, trans-acting factors and environmental stimuli that affect polyadenylation efficiency and/or relative usage of two alternative polyadenylation (APA) sites. The current protein-based CAT...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Expression Regulation
Share to Gene Order

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Reporter

Share to Genetic Vectors

Share to Nucleotide Motifs

Share to Poly A

Share to Polyadenylation

Share to Regulatory Sequences, Nucleic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 29342112
DOI: 10.3390/ijms19010279
PMCID: PMC5796225

Genes

CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Useful Bicistronic Reporter System for Studying Poly(A) Site-Defining cis Elements and Regulation of Alternative Polyadenylation.PMID 29342112Read ↗

Alternative cleavage and polyadenylation: key regulatory mechanisms in health and diseaseSemantic proximity Read ↗

Plant polyadenylation factors: conservation and variety in the polyadenylation complex in plants.Semantic proximity Read ↗

Effects of the multiple polyadenylation signal AAUAAA on mRNA 3'-end formation and gene expression.Semantic proximity Read ↗

Viral Hijacking of Host Polyadenylation Machinery to Regulate Post-Transcriptional Gene ExpressionSemantic proximity Read ↗

Divergence in alternative polyadenylation contributes to gene regulatory differences between humans and chimpanzeesSemantic proximity Read ↗

Systematic evaluation of the effect of polyadenylation signal variants on the expression of disease-associated genes.Semantic proximity Read ↗

PABPN1 shuts down alternative poly(A) sites.Semantic proximity Read ↗

Patterns of variant polyadenylation signal usage in human genes.Semantic proximity Read ↗

Characterization of the Role of Hexamer AGUAAA and Poly(A) Tail in Coronavirus Polyadenylation.Semantic proximity Read ↗

Identification and characterization of polyadenylation signal (PAS) variants in human genomic sequences based on modified EST clustering.Semantic proximity Read ↗

The poly(A)-binding protein nuclear 1 suppresses alternative cleavage and polyadenylation sites.Semantic proximity Read ↗

Single nucleotide polymorphisms can create alternative polyadenylation signals and affect gene expression through loss of microRNA-regulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.