Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of the Role of Hexamer AGUAAA and Poly(A) Tail in Coronavirus Polyadenylation.

PloS one - 1 Jan 2016

Peng Yu-Hui, Lin Ching-Houng, Lin Chao-Nan, Lo Chen-Yu, Tsai Tsung-Lin, Wu Hung-Yi

Abstract excerpt

Similar to eukaryotic mRNA, the positive-strand coronavirus genome of ~30 kilobases is 5'-capped and 3'-polyadenylated. It has been demonstrated that the length of the coronaviral poly(A) tail is not static but regulated during infection; however, little is known regarding the factors involved in coronaviral polyadenylation and its regulation. Here, we show that during infection, the level of coronavirus poly(A)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to Coronavirus
Share to Coronavirus Infections

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Mutation

Share to Polyadenylation

Share to RNA, Messenger

Share to RNA, Viral

Source

Open in PubMed Open full text

Identifiers

PMID: 27760233
DOI: 10.1371/journal.pone.0165077
PMCID: PMC5070815

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of the Role of Hexamer AGUAAA and Poly(A) Tail in Coronavirus Polyadenylation.PMID 27760233Read ↗

Viral Hijacking of Host Polyadenylation Machinery to Regulate Post-Transcriptional Gene ExpressionSemantic proximity Read ↗

Regulation of coronaviral poly(A) tail length during infection.Semantic proximity Read ↗

In Vivo Addition of Poly(A) Tail and AU-Rich Sequences to the 3′ Terminus of the Sindbis Virus RNA Genome: a Novel 3′-End Repair PathwaySemantic proximity Read ↗

Effects of the multiple polyadenylation signal AAUAAA on mRNA 3'-end formation and gene expression.Semantic proximity Read ↗

Effect of RNA secondary structure on polyadenylation site selection.Semantic proximity Read ↗

Full-length mRNA sequencing reveals principles of poly(A) tail length controlSemantic proximity Read ↗

Implications of Poly(A) Tail Processing in Repeat Expansion DiseasesSemantic proximity Read ↗

Structures and Functions of the 3′ Untranslated Regions of Positive-Sense Single-Stranded RNA Viruses Infecting Humans and AnimalsSemantic proximity Read ↗

Useful Bicistronic Reporter System for Studying Poly(A) Site-Defining cis Elements and Regulation of Alternative Polyadenylation.Semantic proximity Read ↗

Destabilization of the TAR hairpin leads to extension of the polyA hairpin and inhibition of HIV-1 polyadenylationSemantic proximity Read ↗

Structural model of the complete poly(A) region of HIV-1 pre-mRNA.Semantic proximity Read ↗

Functional annotation of human cytomegalovirus gene products: an updateSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.