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Article

Patterns of variant polyadenylation signal usage in human genes.

Genome research - 1 Jul 2000

Beaudoing E, Freier S, Wyatt J R, Claverie J M, Gautheret D

Abstract excerpt

The formation of mature mRNAs in vertebrates involves the cleavage and polyadenylation of the pre-mRNA, 10-30 nt downstream of an AAUAAA or AUUAAA signal sequence. The extensive cDNA data now available shows that these hexamers are not strictly conserved. In order to identify variant polyadenylation signals on a large scale, we compared over 8700 human 3' untranslated sequences to 157,775 polyadenylated expressed...

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Identifiers

PMID: 10899149
DOI: 10.1101/gr.10.7.1001
PMCID: PMC310884

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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