Article
Slc11a1 (formerly NRAMP1) gene modulates both acute inflammatory reactions and pristane-induced arthritis in mice.
Genes and immunity - 1 Jan 2007
Peters L C, Jensen J R, Borrego A, Cabrera W H K, Baker N, Starobinas N, Ribeiro O G, Ibañez O M, De Franco M
Abstract excerpt
Mice selected for the maximum acute inflammatory reaction (AIRmax) are highly susceptible to pristane-induced arthritis (PIA), whereas mice selected for the minimum response (AIRmin) are resistant. These lines show distinct patterns of leukocyte infiltration and R and S allele frequency disequilibrium of the solute carrier family 11a member 1 (Slc11a1) gene. In order to study the interactions of the Slc11a1 R and...
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