Pristane-induced arthritis in the rat.

doi:10.1007/978-1-59745-402-5_19

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Article

Pristane-induced arthritis in the rat.

Methods in molecular medicine - 1 Jan 2007

Olofsson Peter, Holmdahl Rikard

Abstract excerpt

A chronic relapsing arthritis develops after a single subcutaneous injection of small amounts of pristane; the pristane induced arthritis (PIA) model in the rat. PIA is characterized by a sudden onset of disease 2 wk after induction. The main pathological features of PIA include edema accompanied by an acute phase response, infiltration into the joint of mononuclear and polymorphonuclear cells, pannus formation,...

Topics

Adjuvants, Immunologic
Adoptive Transfer
Animals
Arthritis, Experimental
Blood Proteins
Glycoproteins
Immunosuppressive Agents
Inflammation
Interleukin-6
Orosomucoid
Phenotype
Rats
Rats, Inbred Strains
T-Lymphocytes
Terpenes

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Open in PubMed

Identifiers

PMID: 17983154
DOI: 10.1007/978-1-59745-402-5_19

Genes

COMP

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