Article
Genetic links between the acute-phase response and arthritis development in rats.
Arthritis and rheumatism - 1 Jan 2002
Olofsson Peter, Nordquist Niklas, Vingsbo-Lundberg Carina, Larsson Anders, Falkenberg Cecilia, Pettersson Ulf, Akerström Bo, Holmdahl Rikard
Abstract excerpt
OBJECTIVE: The acute-phase inflammatory response is closely correlated with the development of rheumatoid arthritis, but the pathophysiologic role of its specific components is largely unknown. We investigated the genetic control of the acute-phase protein response in pristane-induced arthritis (PIA), which is a chronic erosive arthritis model in rats. METHODS: Plasma levels of the acute-phase proteins...
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