Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Slc11a1 (Nramp1) alleles interact with acute inflammation loci to modulate wound-healing traits in mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 2007

De Franco Marcelo, Carneiro Patrícia dos Santos, Peters Luciana Carla, Vorraro Francisca, Borrego Andrea, Ribeiro Orlando Garcia, Starobinas Nancy, Cabrera Wafa Koury, Ibañez Olga Martinez

Abstract excerpt

Lines of mice were obtained by selective breeding for maximum (AIRmax) or minimum (AIRmin) acute inflammation. They present distinct neutrophil influx and show frequency disequilibrium of the solute carrier family 11a member 1 (Slc11a1) alleles. This gene is involved in ion transport at the endosomes within macrophages and neutrophils, interfering in their activation. Homozygous AIRmax and AIRmin sublines for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cation Transport Proteins
Share to Crosses, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Markers

Share to Inflammation

Share to Quantitative Trait, Heritable

Share to Quantitative Trait Loci

Share to Time Factors

Share to Wound Healing

Source

Identifiers

PMID: 17486412
DOI: 10.1007/s00335-007-9012-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Slc11a1 (Nramp1) alleles interact with acute inflammation loci to modulate wound-healing traits in mice.PMID 17486412Read ↗

Slc11a1 (formerly NRAMP1) gene modulates both acute inflammatory reactions and pristane-induced arthritis in mice.Semantic proximity Read ↗

Distinct early inflammatory events during ear tissue regeneration in mice selected for high inflammation bearing Slc11a1 R and S alleles.Semantic proximity Read ↗

Pristane-induced arthritis loci interact with the Slc11a1 gene to determine susceptibility in mice selected for high inflammation.Semantic proximity Read ↗

Genetic determinants of acute inflammation regulate Salmonella infection and modulate Slc11a1 gene (formerly Nramp1) effects in selected mouse lines.Semantic proximity Read ↗

Slc11a1 gene polymorphism influences dextran sulfate sodium (DSS)-induced colitis in a murine model of acute inflammationSemantic proximity Read ↗

A new model of outbred genetically selected mice which present a strong acute inflammatory response in the absence of complement component C5.Semantic proximity Read ↗

Genetic mapping in Diversity Outbred mice identifies a <i>Trpa1</i> variant influencing late phase formalin responseSemantic proximity Read ↗

Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line.Semantic proximity Read ↗

Genetic analysis of a mammalian wound-healing trait.Semantic proximity Read ↗

Association study by genetic clustering detects multiple inflammatory response loci in non-inbred mice.Semantic proximity Read ↗

Genetic and functional evidence for a role for SLC11A1 in susceptibility to otitis media in early childhood in a Western Australian population.Semantic proximity Read ↗

Pulmonary adenoma susceptibility 1 (Pas1) locus affects inflammatory response.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.