Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevalence of UGT1A9 and UGT2B7 nonsynonymous single nucleotide polymorphisms in West African, Papua New Guinean, and North American populations.

European journal of clinical pharmacology - 1 Jan 2007

Mehlotra Rajeev K, Bockarie Moses J, Zimmerman Peter A

Abstract excerpt

OBJECTIVE: UDP-glucuronosyltransferases (UGTs) UGT1A9 and UGT2B7 are involved in the metabolism of antimalarial dihydroartemisinin and antiretroviral zidovudine. Our aim was to analyze the prevalence of UGT1A9 (chromosome 2) and UGT2B7 (chromosome 4) nonsynonymous single nucleotide polymorphisms (SNPs) in West African (WA), Papua New Guinean (PNG), and North American (NA) populations. METHODS: Using a post-PCR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endemic Diseases
Share to Glucuronosyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hispanic or Latino

Share to Malaria

Share to North America

Share to Papua New Guinea

Share to Population Groups

Share to UDP-Glucuronosyltransferase 1A9

Source

Open in PubMed Open full text

Identifiers

PMID: 17115150
DOI: 10.1007/s00228-006-0206-z
PMCID: PMC2577308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevalence of UGT1A9 and UGT2B7 nonsynonymous single nucleotide polymorphisms in West African, Papua New Guinean, and North American populations.PMID 17115150Read ↗

Prevalence of CYP2B6 alleles in malaria-endemic populations of West Africa and Papua New Guinea.Semantic proximity Read ↗

Worldwide variation in human drug-metabolism enzyme genes CYP2B6 and UGT2B7: implications for HIV/AIDS treatment.Semantic proximity Read ↗

Pharmacogenomics in Papua New Guineans: unique profiles and implications for enhancing drug efficacy while improving drug safety.Semantic proximity Read ↗

Relationship between metabolic phenotypes and genotypes of CYP1A2 and CYP2A6 in the Nigerian population.Semantic proximity Read ↗

CYP2B6 983T>C polymorphism is prevalent in West Africa but absent in Papua New Guinea: implications for HIV/AIDS treatment.Semantic proximity Read ↗

CYP2D6 genotyping analysis and functional characterization of novel allelic variants in a Ni-Vanuatu and Kenyan population by assessing dextromethorphan O-demethylation activity.Semantic proximity Read ↗

Genotype and allele frequencies of polymorphic UGT1A9 in the Polish population.Semantic proximity Read ↗

Pharmacogenetics of CYP2B6, CYP2A6 and UGT2B7 in HIV treatment in African populations: focus on efavirenz and nevirapine.Semantic proximity Read ↗

A Review of Pharmacogenetics of Antimalarials and Associated Clinical Implications.Semantic proximity Read ↗

Human UGT1A6 pharmacogenetics: identification of a novel SNP, characterization of allele frequencies and functional analysis of recombinant allozymes in human liver tissue and in cultured cells.Semantic proximity Read ↗

CYP3A4*1B and NAT2*14 alleles in a native African population.Semantic proximity Read ↗

UGT2B7 c.-161C>T polymorphism frequency in Croatian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.