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Pharmacogenomics in Papua New Guineans: unique profiles and implications for enhancing drug efficacy while improving drug safety.

Pharmacogenetics and genomics - 1 Jun 2018

Tucci Joseph D, Pumuye Paul P, Helsby Nuala A, Barratt Daniel T, Pokeya Percy P, Hombhanje Francis, Somogyi Andrew A

Abstract excerpt

Papua New Guinea (PNG) can be roughly divided into highland, coastal and island peoples with significant mitochondrial DNA differentiation reflecting early and recent distinct migrations from Africa and East Asia, respectively. Infectious diseases such as tuberculosis, malaria and HIV severely impact on the health of its peoples for which drug therapy is the major treatment and pharmacogenetics has clinical...

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PMID: 29768302
DOI: 10.1097/FPC.0000000000000335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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