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Article

Prevalence of CYP2B6 alleles in malaria-endemic populations of West Africa and Papua New Guinea.

European journal of clinical pharmacology - 1 Apr 2006

Mehlotra Rajeev K, Ziats Mark N, Bockarie Moses J, Zimmerman Peter A

Abstract excerpt

OBJECTIVE: Cytochrome P450 2B6 (CYP2B6) is involved in the metabolism of artemisinin drugs, a novel series of antimalarials. Our aim was to analyze the prevalence of the most commonly observed CYP2B6 alleles in malaria-endemic populations of West Africa (WA) and Papua New Guinea (PNG). METHODS: Using a post-PCR ligation detection reaction-fluorescent microsphere assay, frequencies of CYP2B6*1A, *2, *3, *4, *5,...

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Identifiers

PMID: 16506047
DOI: 10.1007/s00228-005-0092-9
PMCID: PMC4450653

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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