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Article

Genotype and allele frequencies of polymorphic UGT1A9 in the Polish population.

European journal of drug metabolism and pharmacokinetics - 1 Sept 2013

Zakerska Oliwia, Skrzypczak-Zielinska Marzena, Mikstacki Adam, Tamowicz Barbara, Malengowska Bianka, Szalata Marlena, Slomski Ryszard

Abstract excerpt

The human UDP-glucuronosyltransferase 1A9 (UGT1A9) plays a central role in the metabolism of different therapeutic drugs, carcinogens and endobiotics. The UGT1A9 gene shows genetic polymorphism with frequencies significantly different in populations and ethnic groups. Many of these genetic variants are directly responsible for polymorphic drug metabolism. Three crucial alleles of UGT1A9, UGT1A9*3 (p.Met33Thr), *4...

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PMID: 23184343
DOI: 10.1007/s13318-012-0110-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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