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Article

A Review of Pharmacogenetics of Antimalarials and Associated Clinical Implications.

European journal of drug metabolism and pharmacokinetics - 1 Oct 2017

Elewa Hazem, Wilby Kyle John

Abstract excerpt

Genetic variability in drug-metabolizing enzymes and drug transporters is known to influence the pharmacokinetics of many drugs. Antimalarial drugs are a class of agents known to utilize metabolic and elimination pathways prone to genetic variation. This paper aims to review the genetic variants affecting antimalarial medications and discuss their clinical implications. Data were identified for the genes coding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28070879
DOI: 10.1007/s13318-016-0399-1

Genes

ABCB1

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