Effect of ermC leader region mutations on induced mRNA stability.

doi:10.1128/jb.173.12.3732-3740.1991

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Article

Effect of ermC leader region mutations on induced mRNA stability.

Journal of bacteriology - 1 Jun 1991

Hue K K, Bechhofer D H

Abstract excerpt

Induction of translation of the ermC gene product in Bacillus subtilis occurs upon exposure to erythromycin and is a result of ribosome stalling in the ermC leader peptide coding sequence. Another result of ribosome stalling is stabilization of ermC mRNA. The effect of leader RNA secondary struct...

Topics

Amino Acid Sequence
Bacillus subtilis
Base Sequence
Erythromycin
Gene Expression Regulation, Bacterial
Genes, Bacterial
Molecular Sequence Data
Mutation
Plasmids
Protein Conformation
Protein Sorting Signals
RNA, Bacterial
RNA, Messenger
Restriction Mapping
Ribosomes
Tylosin

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