Article
Transcriptional attenuation control of ermK, a macrolide-lincosamide-streptogramin B resistance determinant from Bacillus licheniformis.
Journal of bacteriology - 1 Aug 1991
Kwak J H, Choi E C, Weisblum B
Abstract excerpt
ermK instructs bacteria to synthesize an erythromycin-inducible 23S rRNA methylase that confers resistance to the macrolide, lincosamide, and streptogramin B antibiotics. Expression of ermK is regulated by transcriptional attenuation, in contrast to other inducible erm genes, previously described...
Topics
- Amino Acid Sequence
- Anti-Bacterial Agents
- Bacillus
- Base Sequence
- Blotting, Northern
- Drug Resistance, Microbial
- Genes, Bacterial
- Lincosamides
- Macrolides
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Peptide Chain Initiation, Translational
- Protein Biosynthesis
- RNA, Messenger