Article
The DRD2 gene in psychiatric and neurological disorders and its phenotypes.
Pharmacogenomics - 1 Aug 2000
Noble E P
Abstract excerpt
The TaqIA D2 dopamine receptor (DRD2) minor (A1) allele was first associated with severe alcoholism a decade ago. Since then, studies both confirming and not confirmnning this finding were reported. However, a meta-analysis of a large number of Caucasian alcoholics (both more severe and less severe) and controls (both assessed and unassessed for substance use disorders) revealed a significantly higher frequency...
Topics
- Animals
- Humans
- Mental Disorders
- Nervous System Diseases
- Phenotype
- Receptors, Dopamine D2