Article
The dopamine D2 receptor (DRD2) gene: a genetic risk factor in smoking.
Pharmacogenetics - 1 Feb 1996
Comings D E, Ferry L, Bradshaw-Robinson S, Burchette R, Chiu C, Muhleman D
Abstract excerpt
Of a group of 312 non-Hispanic Caucasians who smoked at least one pack per day, had unsuccessfully attempted to stop smoking, and were free of alcohol or other drug dependence, 48.7% carried the A1 allele of the DRD2 gene. This was significantly greater than the 25.9% prevalence in the 714 known non-Hispanic Caucasian controls without alcohol or drug abuse, p < 10(-8), and significantly greater than in a smaller...
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