Article
Prevalence of two tumor necrosis factor gene polymorphisms in premature infants with early onset sepsis.
Biology of the neonate - 1 Jan 2006
Schueller A C, Heep A, Kattner E, Kroll M, Wisbauer M, Sander J, Bartmann P, Stuber F
Abstract excerpt
BACKGROUND: Tumor necrosis factor (TNF) is a central mediator of sepsis. The NcoI polymorphism within the TNF locus has been described as a prognostic marker for mortality in adult patients with sepsis. OBJECTIVES: The aim of our study was to investigate the genotype and allele distribution of 2 TNF gene polymorphisms in preterm infants <32 weeks of gestational age, who developed early-onset sepsis. METHODS: A...
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