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Article

Evaluation of TNF-α genetic polymorphisms as predictors for sepsis susceptibility and progression.

BMC infectious diseases - 14 Mar 2020

Georgescu Anca Meda, Banescu Claudia, Azamfirei Razvan, Hutanu Adina, Moldovan Valeriu, Badea Iudita, Voidazan Septimiu, Dobreanu Minodora, Chirtes Ioana Raluca, Azamfirei Leonard

Abstract excerpt

BACKGROUND: The goal of the study was to evaluate a potential role for tumor necrosis factor alpha (TNF-α) genetic variability as biomarker in sepsis. In particular, we aimed to determine if single nucleotide polymorphisms (SNPs) of TNF-α gene are associated with sepsis in terms of risk, severity and outcome. METHODS: We performed a prospective study on 163 adult critically ill septic patients (septic shock 65,...

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Identifiers

PMID: 32171247
DOI: 10.1186/s12879-020-4910-6
PMCID: PMC7071754

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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