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Article

TNF-α, IL-6, and IL-8 cytokines and their association with TNF-α-308 G/A polymorphism and postoperative sepsis.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Aug 2014

Baghel Kavita, Srivastava Rajeshwar Nath, Chandra Abhijit, Goel Sudhir K, Agrawal Jyotsna, Kazmi Hasan Raza, Raj Saloni

Abstract excerpt

INTRODUCTION: Early prediction of postoperative sepsis remains an enormous clinical challenge. Association of TNF-α-308 G/A polymorphism with sepsis remains controversial. We, therefore, investigated this polymorphism with serum levels of cytokines TNF-α, IL-6, and IL-8 in relation to development of sepsis following major gastrointestinal surgery. METHODS: Two hundred and thirty-nine patients undergoing major...

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PMID: 24944154
DOI: 10.1007/s11605-014-2574-5

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TNF

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