Article
Variation within the human killer cell immunoglobulin-like receptor (KIR) gene family.
Critical reviews in immunology - 1 Jan 2002
Yawata Makoto, Yawata Nobuyo, Abi-Rached Laurent, Parham Peter
Abstract excerpt
The killer cell immunoglobulin-like receptors (KIR) form a family of highly homologous immune receptors that regulate the response of natural killer (NK) cells and some T cells. The genetics of the human KIR family is reviewed in this article. In human populations, diversity in KIR genotype arises from variations in gene content and allelic polymorphism. Comparisons of 81 human KIR sequences reveal past events...
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