Article
2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells.
Genes and immunity - 1 Jan 2000
Dunphy S E, Guinan K J, Chorcora C Ní, Jayaraman J, Traherne J A, Trowsdale J, Pende D, Middleton D, Gardiner C M
Abstract excerpt
Natural killer (NK) cells are lymphocytes that function as part of the innate immune system. Their activity is controlled by a range of inhibitory and activating receptors, including the important killer-cell immunoglobulin-like receptors (KIR). The KIR are a multi-gene family of receptors that interact with the human leukocyte antigen (HLA) class I family of molecules and are characterised by extensive allelic...
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