Article
Familial Alzheimer disease in Latinos: interaction between APOE, stroke, and estrogen replacement.
Neurology - 10 Jan 2006
Rippon G A, Tang M X, Lee J H, Lantigua R, Medrano M, Mayeux R
Abstract excerpt
BACKGROUND: Factors that modify risk related to APOE variants have been examined primarily in unrelated patients and controls, but seldom in family-based studies. Stroke, vascular risk factors, estrogen replacement therapy (ERT), head injury (HI), and smoking have been reported to influence risk of sporadic but not familial Alzheimer disease (AD). OBJECTIVES: To examine the potential relationship between these...
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