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Article

APOE-epsilon4 count predicts age when prevalence of AD increases, then declines: the Cache County Study.

Neurology - 22 Jul 1999

Breitner J C, Wyse B W, Anthony J C, Welsh-Bohmer K A, Steffens D C, Norton M C, Tschanz J T, Plassman B L, Meyer M R, Skoog I, Khachaturian A

Abstract excerpt

OBJECTIVE: To examine the prevalence of Alzheimer's disease (AD) and other dementias in relation to age, education, sex, and genotype at APOE. Recent studies suggest age heterogeneity in the risk of AD associated with the APOE genotype and a possible interaction between APOE-epsilon4 and female sex as risk factors. We studied these topics in the 5,677 elderly residents of Cache County, Utah, a population known...

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Source

Identifiers

PMID: 10430421
DOI: 10.1212/wnl.53.2.321

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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