Article
Low temperature and peptides favor the formation of class I heterodimers on RMA-S cells at the cell surface.
Proceedings of the National Academy of Sciences of the United States of America - 15 May 1991
Rock K L, Gramm C, Benacerraf B
Abstract excerpt
RMA-S murine cells have a mutation that interferes with the assembly of class I major histocompatibility complex (MHC) heterodimers and are deficient in the expression of class I molecules on the cell surface. The mutant phenotype has been reported to be normalized upon incubation of RMA-S cells...
Topics
- Animals
- Blood
- Cold Temperature
- Epitopes
- Histocompatibility Antigens Class I
- Immunosorbent Techniques
- Lymphoma
- Macromolecular Substances
- Mice
- Mice, Inbred C57BL
- Mutation
- Tumor Cells, Cultured
- beta 2-Microglobulin