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Article

FAK phosphorylation at Ser-843 inhibits Tyr-397 phosphorylation, cell spreading and migration.

Journal of cellular physiology - 1 Feb 2007

Jacamo Rodrigo, Jiang Xiaohua, Lunn J Adrian, Rozengurt Enrique

Abstract excerpt

Multiple stimuli promote the tyrosine phosphorylation and activation of focal adhesion kinase (FAK), which ultimately facilitates migration. Little is known about the effect of adhesion-dependent signals and cytoskeleton organization on the regulation of FAK phosphorylation at serine sites, or about the role of FAK serine phosphorylation in cell migration. Here, we show that FAK phosphorylation at Ser-843 is...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17096371
DOI: 10.1002/jcp.20870

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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