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Article

MARCKS regulates membrane ruffling and cell spreading.

Current biology : CB - 1 Aug 1997

Myat M M, Anderson S, Allen L A, Aderem A

Abstract excerpt

The dynamic rearrangement of the actin cytoskeleton is fundamental to most biological processes including embryogenesis, morphogenesis, cell movement, wound healing and metastasis [1]. Membrane ruffling and reversible cell-substratum interactions underlie actin-driven cell movement. Protein kinas...

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Source

Identifiers

PMID: 9259558
DOI: 10.1016/s0960-9822(06)00262-4

Genes

MARCKS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9259558-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

MARCKS regulates membrane ruffling and cell spreading.PMID 9259558Read ↗

Integrin signaling via FAK-Src controls cytokinetic abscission by decelerating PLK1 degradation and subsequent recruitment of CEP55 at the midbodySemantic proximity Read ↗

FAK phosphorylation at Ser-843 inhibits Tyr-397 phosphorylation, cell spreading and migration.Semantic proximity Read ↗

Involvement of protein phosphatase-1-mediated MARCKS translocation in myogenic differentiation of embryonic muscle cells.Semantic proximity Read ↗

Kinase-dependent adhesion to fibronectin: regulation by calreticulin.Semantic proximity Read ↗

Protein kinase Cepsilon-dependent MARCKS phosphorylation in neonatal and adult rat ventricular myocytes.Semantic proximity Read ↗

Role of MacMARCKS in integrin-dependent macrophage spreading and tyrosine phosphorylation of paxillin.Semantic proximity Read ↗

Protein kinase C regulates MARCKS cycling between the plasma membrane and lysosomes in fibroblasts.Semantic proximity Read ↗

Two myristoylated alanine-rich C-kinase substrate (MARCKS) paralogs are required for normal development in zebrafish.Semantic proximity Read ↗

Myristoylation alters retinoic acid-induced down-regulation of MARCKS in immortalized hippocampal cells.Semantic proximity Read ↗

Essential roles of Crk and CrkL in fibroblast structure and motility.Semantic proximity Read ↗

Macrophage-enriched myristoylated alanine-rich C kinase substrate and its phosphorylation is required for the phorbol ester-stimulated diffusion of beta 2 integrin molecules.Semantic proximity Read ↗

v-Src accelerates spontaneous motility via phosphoinositide 3-kinase, phospholipase C and phospholipase D, but abrogates chemotaxis in Rat-1 and MDCK cells.Semantic proximity Read ↗

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