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Article

Insulin-like growth factor-1 genotypes and haplotypes influence the survival of prostate cancer patients with bone metastasis at initial diagnosis.

BMC cancer - 25 Mar 2013

Tsuchiya Norihiko, Narita Shintaro, Inoue Takamitsu, Saito Mitsuru, Numakura Kazuyuki, Huang Mingguo, Hatakeyama Shingo, Satoh Shigeru, Saito Seiichi, Ohyama Chikara, Arai Yoichi, Ogawa Osamu, Habuchi Tomonori

Abstract excerpt

BACKGROUND: The insulin-like growth factor-1 (IGF-1) plays an important role in growth of prostate cancer (PCa) cells and facilitating the development and progression of PCa. This study aimed to evaluate the association of polymorphisms in three linkage disequilibrium (LD) blocks of the IGF-1 on the survival of metastatic PCa patients. METHODS: A total of 215 patients with bone metastases at initial presentation...

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Identifiers

PMID: 23530598
DOI: 10.1186/1471-2407-13-150
PMCID: PMC3622563

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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