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Article

Common variants in IGF1 pathway genes and clinical outcomes after radical prostatectomy.

Annals of surgical oncology - 1 Jul 2013

Chang Chi-Fen, Pao Jiunn-Bey, Yu Chia-Cheng, Huang Chao-Yuan, Huang Shu-Pin, Yang Ying-Pi, Huang Chun-Nung, Chang Ta-Yuan, You Bang-Jau, Lee Hong-Zin, Hour Tzyh-Chyuan, Bao Bo-Ying

Abstract excerpt

BACKGROUND: Insulin-like growth factor-1 (IGF1) pathway plays a critical role in malignant transformation, and epidemiology studies have also shown that single nucleotide polymorphisms (SNPs) in IGF1 pathway genes are associated with prostate cancer risk. However, the clinical significance of these SNPs on prostate cancer aggressiveness and prognosis after radical prostatectomy (RP) has not been determined....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23397154
DOI: 10.1245/s10434-013-2884-y

Genes

IGF1

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