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Article

The ghrelin/obestatin balance in the physiological and pathological control of growth hormone secretion, body composition and food intake.

Journal of neuroendocrinology - 1 Jul 2010

Hassouna R, Zizzari P, Tolle V

Abstract excerpt

Ghrelin and obestatin are two gastrointestinal peptides obtained by post-translational processing of a common precursor, preproghrelin. Ghrelin is an orexigenic and adipogenic peptide and a potent growth hormone secretagogue (GHS) modified by the enzyme ghrelin-O-acyl-transferase to bind and activate its receptor, the GHS-R. The ghrelin/GHS-R pathway is complex and the effects of ghrelin on GH secretion,...

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Source

Identifiers

PMID: 20456603
DOI: 10.1111/j.1365-2826.2010.02019.x

Genes

GPR39

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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