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Article

The involvement of replication in single stranded oligonucleotide-mediated gene repair.

Nucleic acids research - 1 Jan 2006

Huen Michael S Y, Li Xin-tian, Lu Lin-Yu, Watt Rory M, Liu De-Pei, Huang Jian-Dong

Abstract excerpt

Targeted gene repair mediated by single-stranded oligonucleotides (SSOs) has great potential for use in functional genomic studies and gene therapy. Genetic changes have been created using this approach in a number of prokaryotic and eukaryotic systems, including mouse embryonic stem cells. Howev...

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Identifiers

PMID: 17088285
DOI: 10.1093/nar/gkl852
PMCID: PMC1693898

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17088285-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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