Article
Yeast Derlin Dfm1 interacts with Cdc48 and functions in ER homeostasis.
Yeast (Chichester, England) - 1 Jan 2000
Sato Brian K, Hampton Randolph Y
Abstract excerpt
Recent studies have identified Derlin-1, a protein that associates with the AAA-ATPase p97 and is implicated in late steps in ER-associated protein degradation (ERAD). Derlin-1 has two Saccharomyces cerevisiae homologues, Der1p and Dfm1p. While Der1p has been studied extensively, little is known about Dfm1p. Accordingly, we investigated the role of Dfm1p in ERAD, ER homeostasis and interactions with the yeast p97...
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