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Article

Derlin-dependent accumulation of integral membrane proteins at cell surfaces.

Journal of cell science - 1 Jul 2009

Schaheen Basil, Dang Hope, Fares Hanna

Abstract excerpt

Quality-control mechanisms of protein folding of transmembrane and secreted proteins is mediated by endoplasmic-reticulum-associated degradation (ERAD), which is used to detect and to degrade misfolded proteins in the ER. The ERAD machinery consists of chaperones, transmembrane proteins and ubiquitin-associated enzymes that detect, modify, and retro-translocate the misfolded proteins to the cytoplasm for...

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Identifiers

PMID: 19509052
DOI: 10.1242/jcs.048892

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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