Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cooperative function of the CHD5-like protein Mdm39p with a P-type ATPase Spf1p in the maintenance of ER homeostasis in Saccharomyces cerevisiae.

Molecular genetics and genomics : MGG - 1 Jul 2005

Ando A, Suzuki C

Abstract excerpt

Spf1p is a P-type ATPase that is mainly localized to the endoplasmic reticulum (ER) in Saccharomyces cerevisiae. The protein is involved in the maintenance of ion homeostasis in the ER. To investigate the intracellular role of Spf1p in more detail, we performed a genetic screen for mutations that lead to synthetic lethality in combination with a disruption of SPF1; the mutations identified have been termed lws...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP-Binding Cassette Transporters
Share to Calcium

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Endoplasmic Reticulum

Share to Genes, Fungal

Share to Genes, Lethal

Share to Glycosylation

Share to Homeostasis

Share to Protein Folding

Source

Identifiers

PMID: 15909163
DOI: 10.1007/s00438-005-1153-6

Genes

CHD5
RIC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cooperative function of the CHD5-like protein Mdm39p with a P-type ATPase Spf1p in the maintenance of ER homeostasis in Saccharomyces cerevisiae.PMID 15909163Read ↗

Cod1p/Spf1p is a P-type ATPase involved in ER function and Ca2+ homeostasis.Semantic proximity Read ↗

Yeast Derlin Dfm1 interacts with Cdc48 and functions in ER homeostasis.Semantic proximity Read ↗

The yeast penta-EF protein Pef1p is involved in cation-dependent budding and cell polarization.Semantic proximity Read ↗

Dsl1p, Tip20p, and the novel Dsl3(Sec39) protein are required for the stability of the Q/t-SNARE complex at the endoplasmic reticulum in yeast.Semantic proximity Read ↗

Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease.Semantic proximity Read ↗

The novel adaptor protein, Mti1p, and Vrp1p, a homolog of Wiskott-Aldrich syndrome protein-interacting protein (WIP), may antagonistically regulate type I myosins in Saccharomyces cerevisiae.Semantic proximity Read ↗

Role for two conserved intermembrane space proteins, Ups1p and Ups2p, [corrected] in intra-mitochondrial phospholipid trafficking.Semantic proximity Read ↗

Structural and functional mapping of Rtg2p determinants involved in retrograde signaling and aging of Saccharomyces cerevisiae.Semantic proximity Read ↗

Genetic Analysis of Calmodulin and Its Targets in <i>Saccharomyces cerevisiae</i>Semantic proximity Read ↗

Identification of Cdc37 as a novel regulator of the stress-responsive mitogen-activated protein kinase.Semantic proximity Read ↗

Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2.Semantic proximity Read ↗

Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.