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Article

Protein C -1641 AA is associated with decreased survival and more organ dysfunction in severe sepsis.

Critical care medicine - 1 Jan 2007

Walley Keith R, Russell James A

Abstract excerpt

OBJECTIVE: Protein C contains an A/G polymorphism at position -1641 and a C/T polymorphism at -1654 associated with risk of deep venous thrombosis. We tested the hypothesis that these polymorphisms are associated with altered outcome in patients having severe sepsis, in which protein C is a central molecule. DESIGN: Prospective cohorts, gene-association study. SETTING: Tertiary care medical/surgical intensive...

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Identifiers

PMID: 17080006
DOI: 10.1097/01.CCM.0000249823.44726.4E

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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