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Article

Protein C -1641A/-1654C haplotype is associated with organ dysfunction and the fatal outcome of severe sepsis in Chinese Han population.

Human genetics - 1 Apr 2008

Chen Qi Xing, Wu Shui Jing, Wang Hai Hong, Lv Chen, Cheng Bao Li, Xie Guo Hao, Fang Xiang Ming

Abstract excerpt

Activation of protein C plays an important role in modulating coagulation as well as inflammation during severe sepsis. The baseline of activated protein C level in patients with severe sepsis showed interindividual variability between survivors and nonsurvivors, and the decreased level of protein C correlated with organ dysfunction and poor outcome. However, there are limited data concerning the genetic...

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Identifiers

PMID: 18247057
DOI: 10.1007/s00439-008-0476-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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