Article
Genetic polymorphisms and sepsis.
Shock (Augusta, Ga.) - 1 Oct 2005
Arcaroli John, Fessler Michael B, Abraham Edward
Abstract excerpt
Sepsis is a polygenic and complex syndrome that is initiated by infection and is characterized by a systemic inflammatory response. Genetic polymorphisms in the immune response to infection have been shown to be associated with clinical outcomes. Functional and association studies involving genetic polymorphisms in essential genes, including Toll-like receptors, cytokines, and coagulation factors, have provided...
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