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Article

Endothelial protein C receptor polymorphisms and risk of severe sepsis in critically ill patients.

Intensive care medicine - 1 Oct 2013

Vassiliou Alice G, Maniatis Nikolaos A, Kotanidou Anastasia, Kallergi Marina, Karystinaki Foteini S, Letsiou Eleftheria, Glynos Constantinos, Kopterides Petros, Vassiliadi Dimitra, Nikitas Nikitas, Dimopoulou Ioanna, Armaganidis Apostolos, Orfanos Stylianos E

Abstract excerpt

PURPOSE: Endothelial protein C receptor (EPCR) is expressed mainly in endothelial cells and is involved in regulation of the cytoprotective and anticoagulant pathways of protein C. We assessed whether haplotypes in the EPCR gene modify the risk of severe sepsis and/or septic shock (SS/SS) development in critically ill patients. METHODS: Three polymorphisms in the EPCR gene were genotyped in 389 Caucasian...

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Identifiers

PMID: 23881209
DOI: 10.1007/s00134-013-3018-5
PMCID: PMC7095157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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