Protein C rs2069912 C allele is associated with increased mortality from severe sepsis in North Americans of East Asian ancestry.

doi:10.1007/s00439-008-0509-5

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Article

Protein C rs2069912 C allele is associated with increased mortality from severe sepsis in North Americans of East Asian ancestry.

Human genetics - 1 Jul 2008

Russell James A, Wellman Hugh, Walley Keith R

Abstract excerpt

Chen et al. found that the CA haplotype of protein C -1654C/T and -1641G/A was associated with increased risk of death and organ dysfunction in Chinese Han patients with severe sepsis (Hum Genet 123:281-287, 2008). We similarly tested for association of the C allele of protein C 673 T/C (rs2069912) (linkage disequilibrium with the CA haplotype, D' = 100%) in a cohort of 100 North American East Asians with severe...

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PMID: 18496716
DOI: 10.1007/s00439-008-0509-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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