Association of p60c-src with polyoma virus middle-T antigen abrogating mitosis-specific activation.

doi:10.1038/350431a0

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Association of p60c-src with polyoma virus middle-T antigen abrogating mitosis-specific activation.

Nature - 4 Apr 1991

Kaech S, Covic L, Wyss A, Ballmer-Hofer K

Abstract excerpt

Polyoma middle-T antigen is required for tumorigenesis in animals and for viral transformation of a variety of cells in culture (reviewed in ref. 1). Middle-T associates with and thereby activates p60c-src, a cellular tyrosine kinase homologous to the oncogene product of Rous sarcoma virus. Activ...

Topics

Animals
Antibodies, Monoclonal
Antigens, Polyomavirus Transforming
Blotting, Western
Cell Cycle
Cell Transformation, Neoplastic
Cells, Cultured
Mice
Mitosis
Mutation
Peptide Mapping
Phosphorylation
Precipitin Tests
Protein-Tyrosine Kinases
Proto-Oncogene Proteins pp60(c-src)

Source

Open in PubMed

Identifiers

PMID: 1707141
DOI: 10.1038/350431a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1707141-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics