Myristylation of pp60c-src is not required for complex formation with polyomavirus middle-T antigen.

doi:10.1128/JVI.64.10.5163-5166.1990

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Article

Myristylation of pp60c-src is not required for complex formation with polyomavirus middle-T antigen.

Journal of virology - 1 Oct 1990

Wyss A, Kaech S, Ballmer-Hofer K

Abstract excerpt

Middle-T antigen (middle-T), the transforming gene product of polyomavirus, associates with several cellular tyrosine kinases, such as pp60c-src. Complex formation leads to kinase activation and is essential for cell transformation. Middle-T-associated as well as uncomplexed pp60c-src is predomin...

Topics

Animals
Antigens, Polyomavirus Transforming
Cell Line
Gene Expression
Mice
Mutation
Myristic Acid
Myristic Acids
Oncogene Protein pp60(v-src)
Plasmids
Polyomavirus
Protein Processing, Post-Translational
Transfection

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