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The half-life of hepatitis B virions

20 Oct 2006

Abstract excerpt

The virion half-life of hepatitis B virus (HBV) is currently estimated at approximately 1 day. This estimate has been obtained from drug perturbation experiments with reverse transcriptase inhibitors. However, the analyses of those experiments have not considered the export of virions produced from preformed mature DNA-containing HBV capsids in infected cells. Data from 3 acutely infected chimpanzees indicates...

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PMID: 17058221
DOI: 10.1002/hep.21364

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