Article
Viral dynamics in vivo: limitations on estimates of intracellular delay and virus decay.
9 Jul 1996
Abstract excerpt
Anti-viral drug treatment of human immunodeficiency virus type I (HIV-1) and hepatitis B virus (HBV) infections causes rapid reduction in plasma virus load. Viral decline occurs in several phases and provides information on important kinetic constants of virus replication in vivo and pharmacodynamical properties. We develop a mathematical model that takes into account the intracellular phase of the viral...
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