Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mathematical modeling of plus-strand RNA virus replication to identify broad-spectrum antiviral treatment strategies

4 Apr 2023

Abstract excerpt

Plus-strand RNA viruses are the largest group of viruses. Many are human pathogens that inflict a socio-economic burden. Interestingly, plus-strand RNA viruses share remarkable similarities in their replication. A hallmark of plus-strand RNA viruses is the remodeling of intracellular membranes to establish replication organelles (so-called "replication factories"), which provide a protected environment for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to Hepatitis C virus research
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37014904
DOI: 10.1371/journal.pcbi.1010423

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mathematical modeling of plus-strand RNA virus replication to identify broad-spectrum antiviral treatment strategiesPMID 37014904Read ↗

Intracellular Hepatitis C Virus Modeling Predicts Infection Dynamics and Viral Protein MechanismsSemantic proximity Read ↗

A Coupled Mathematical Model of the Intracellular Replication of Dengue Virus and the Host Cell Immune Response to InfectionSemantic proximity Read ↗

Replication Vesicles are Load- and Choke-Points in the Hepatitis C Virus LifecycleSemantic proximity Read ↗

Dengue Virus- and Hepatitis C Virus-Induced Replication and Assembly Compartments: the Enemy Inside—Caught in the WebSemantic proximity Read ↗

The Virus-Host Interplay: Biogenesis of +RNA Replication ComplexesSemantic proximity Read ↗

Molecular Insights into the Flavivirus Replication ComplexSemantic proximity Read ↗

Insights into Dengue Virus Genome ReplicationSemantic proximity Read ↗

The Multiples Fates of the Flavivirus RNA Genome During PathogenesisSemantic proximity Read ↗

Compartmentalized replication organelle of flavivirus at the ER and the factors involvedSemantic proximity Read ↗

Replicating without stress: a dengue replicon model reveals distinct host rewiring to accommodate persistenceSemantic proximity Read ↗

Roadblocks and fast tracks: How RNA binding proteins affect the viral RNA journey in the cellSemantic proximity Read ↗

MHV-A59 ORF1a replicase protein nsp7-nsp10 processing in replication.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.