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Estimating hepatitis B virus cccDNA persistence in chronic infection

2020-02-07

Abstract excerpt

Hepatitis B virus (HBV) infection is a major global health problem with over 240 million infected individuals at risk of developing progressive liver disease and hepatocellular carcinoma. HBV is an enveloped DNA virus that establishes its genome as an episomal, covalently closed circular DNA (cccDNA) in the nucleus of infected hepatocytes. Currently available standard-of-care treatments for chronic hepatitis B (CH...

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Literature Corpus work
6219b3ce-1e78-5168-ab24-2e7bf51f4843
DOI
10.1101/2020.02.04.20020362
Open publication

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Estimating hepatitis B virus cccDNA persistence in chronic infectionDOI 10.1101/2020.02.04.20020362
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