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Article

Regulation of c-Src activity by the expression of wild-type v-Src and its kinase-dead double Y416F-K295N mutant.

Archives of biochemistry and biophysics - 15 Nov 2006

Vojtechová Martina, Senigl Filip, Sloncová Eva, Tuhácková Zdena

Abstract excerpt

Active, wild-type v-Src and its kinase-dead double Y416F-K295N mutant were expressed in hamster fibroblasts. Expression of the active v-Src induced activation of endogenous c-Src and increased general protein-tyrosine phosphorylation in the infected cells. Expression of the kinase-dead mutant ind...

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Share to CSK Tyrosine-Protein Kinase
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Share to Oncogene Protein pp60(v-src)

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Source

Identifiers

PMID: 17056000
DOI: 10.1016/j.abb.2006.09.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17056000-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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