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Article

SH3 domains specifically regulate kinase activity of expressed Src family proteins.

The Journal of biological chemistry - 6 Jan 1995

Abrams C S, Zhao W

Abstract excerpt

The Src homology 2 (SH2) and Src homology 3 (SH3) domain are approximately 50% conserved in various Src family kinase members. Several lines of evidence suggest that in Src these domains are sequence motifs that direct substrate recognition, regulate kinase activity, or control subcellular localization. We sought to investigate the function of the homology domains in human Lyn, and to determine whether the...

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PMID: 7529230
DOI: 10.1074/jbc.270.1.333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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