Article
Fitness effects of beneficial mutations: the mutational landscape model in experimental evolution.
Current opinion in genetics & development - 1 Dec 2006
Betancourt Andrea J, Bollback Jonathan P
Abstract excerpt
The mutational landscape model is a theoretical model describing sequence evolution in natural populations. However, recent experimental work has begun to test its predictions in laboratory populations of microbes. Several of these studies have focused on testing the prediction that the effects of beneficial mutations should be roughly exponentially distributed. The prediction appears to be borne out by most of...
Topics
- Adaptation, Biological
- Evolution, Molecular
- Models, Genetic
- Mutation
- Selection, Genetic
