Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The distribution of fitness effects among beneficial mutations in Fisher's geometric model of adaptation.

Journal of theoretical biology - 21 Jan 2006

Orr H Allen

Abstract excerpt

Recent models of adaptation at the DNA sequence level assume that the fitness effects of new mutations show certain statistical properties. In particular, these models assume that the distribution of fitness effects among new mutations is in the domain of attraction of the so-called Gumbel-type extreme value distribution. This assumption has not, however, been justified on any biological or theoretical grounds....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Physiological
Share to Computer Simulation
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Models, Genetic

Share to Mutation

Share to Phenotype

Share to Selection, Genetic

Share to Statistical Distributions

Source

Identifiers

PMID: 15990119
DOI: 10.1016/j.jtbi.2005.05.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The distribution of fitness effects among beneficial mutations in Fisher's geometric model of adaptation.PMID 15990119Read ↗

A general extreme value theory model for the adaptation of DNA sequences under strong selection and weak mutation.Semantic proximity Read ↗

The distribution of fitness effects among beneficial mutations.Semantic proximity Read ↗

Testing the extreme value domain of attraction for distributions of beneficial fitness effects.Semantic proximity Read ↗

The probability of improvement in Fisher's geometric model: a probabilistic approach.Semantic proximity Read ↗

Fisher's geometric model with a moving optimum.Semantic proximity Read ↗

Fitness effects of beneficial mutations: the mutational landscape model in experimental evolution.Semantic proximity Read ↗

Properties of selected mutations and genotypic landscapes under Fisher's geometric model.Semantic proximity Read ↗

Evolving a favorable distribution for mutation effects.Semantic proximity Read ↗

The fitness effect of mutations across environments: Fisher's geometrical model with multiple optima.Semantic proximity Read ↗

Determining the distribution of fitness effects using a generalized Beta-Burr distribution.Semantic proximity Read ↗

Distributions of beneficial fitness effects in RNA.Semantic proximity Read ↗

The evolutionary genetics of adaptation: a simulation study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.